Butein cell cycle

Author: ljwp

August undefined, 2024

WebAllowing NF-κB to enter the nucleus and regulate cell cycle and apoptosis-related gene expression . Several studies have examined the effect of chalcones on NF-κB signaling as a plausible way to modulate inflammation and cancer, and found that several natural chalcones, e.g., butein (16), calomelanone (17), ... WebMar 23, 2024 · In ovarian cancer, butein inhibited cell proliferation, migration, and invasion, and induced cell cycle arrest and apoptosis. In addition, it decreased the growth of ovarian cancer cells in xenograft tumor models. Butein inhibited STAT3 phosphorylation and induced FoxO3a accumulation in the nucleus by inhibiting IL-6 signaling.

Attenuation of Endoplasmic Reticulum Stress Enhances Carvacrol …

WebApr 5, 2016 · In this study, we investigated the anti-leukemic activity of butein and its action mechanisms in ALL. Butein was found to significantly suppress the cellular proliferation … WebButein. Butein (20, 40, 3, 4-tetrahydroxychalcone), is a chalcone that has exhibited a wide range of pharmacological effects such as antiinflammatory, anticancer, antioxidant, and … 5g 用户面功能

Butein Inhibits Cell Proliferation and Induces Cell Cycle Arrest in ...

WebMar 23, 2024 · Butein suppressed downstream signal transduction through higher binding affinity to IL-6. In ovarian cancer, butein inhibited cell proliferation, migration, and … WebCell Research: Cell lines: Human hepatoma cells HepG2 Concentrations: ~50 μM Incubation Time: 1 days Method: The cells (5× 10 3 /mL) are incubated in triplicate in a 96-well plate in the presence or absence of indicated concentration of Butein in a final volume of 0.2 mL for different time intervals at 37 ℃. Thereafter, 20 μL MTT solution (5 mg/mL in … Web4、tin.2 2) FoxO3a and its downstream molecules play a role in the synergistic effects of butein and cisplatin.23) Butein suppresses cell proliferation and enhances apoptosis in paclitaxel-resistant ovarian cancer cells.34) Butein activates FOXO3a/p27kip1 pathway in ALL cell lines.45) Butein inhibited . 5g 生産現場

Butein Inhibits Cell Growth by Blocking the IL-6/IL …

Butein activates p53 in hepatocellular carcinoma cells via blocking ...

WebSurvivin plays a crucial role in G2/M cell cycle transition and apoptosis inhibition8 ... ˜e cells were treated with Butein, and the whole-cell extract (WCE) was prepared using the commercial ... WebFeb 7, 2024 · The role of butein in cell cycle distribution was analyzed using the propidium iodide (PI)/RNase staining buffer. Briefly, the cells were incubated in 6-well plates and … 5g 産業分野WebButein is a chalcone derivative that can be isolated from various plants, including Rhus verniciflua Stokes, Semecarpus anacardium, and Dalbergia odorifera. ... obtusa, Thuja plicata, and Thujopsis dolabrata var. hondai. Yang et al. showed that hinokitiol exposure resulted in cell cycle arrest at the S phase and DNA damage response in both the ... 5g 用戶數

"WebJun 4, 2024 · It was found that butein notably inhibited cell viability, colony formation, migration and invasion, induced cell cycle at the G2/M stage and cell apoptosis, as well as enhanced caspase-3, -8 and -9 activity in HeLa cells in a dose-dependent manner. " - Butein cell cycle

Butein cell cycle

Butein: From ancient traditional remedy to modern nutraceutical

WebDownload scientific diagram Butein induced cell cycle arrest and inhibited the activation of CDK2-Cyclin E complex in RS4-11 and MOLT-4 cells. A. Cells were treated with 0, 50 or 100 μM butein ... WebButein had shown profound efficacy against HCC cells in vitro, and p53 was significantly stabilized and activated after butein treatment. The activation of p53 by butein was …

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WebButene, also known as butylene, is an alkene with the formula C 4 H 8.The word butene may refer to any of the individual compounds. They are colourless gases that are present in …

WebButein is a chalcone of the chalconoids. It can be found in Toxicodendron vernicifluum (or formerly Rhus verniciflua ), Dahlia , Butea ( Butea monosperma ) and Coreopsis [1] It … Web(B) The clonogenicity of A549 and PC-9 cells after butein treatment. the results are expressed as mean ± SEM, n=6. a P < 0.05 versus control group, b P < 0.05 versus 5 μM butein group, c P < 0. ...

WebDec 1, 2024 · Butein is a polyphenol which has high chemotherapeutic potential. Hence, understanding its pharmacokinetic profile will help us to get more molecular insights and optimize its applications in the field of cancer. ... Apoptosis or programmed cell death is a biological feature, of which dysregulation along with cell cycle abnormality are common ... WebButein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a. Butein is a SIRT1 activator (STAC). - Mechanism of …

www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov Lapatinib, a dual EGFR/HER2 tyrosine kinase inhibitor, has been shown to …

WebIntroduction. Genomic instability, a tendency of gene alteration during the life cycle of cells, is considered to be the major driving force of tumorigenesis. 1 The genes engaged in the regulation of cell cycle arrest and DNA damage repair are considered to have an important role to maintain the stability of whole genome. 2 p53, a transcription factor which is often … 5g 発熱問題WebMar 1, 2015 · Induces cell-cycle arrest and apoptosis in A549 cells, by downregulating COX-2 mRNA and protein levels: ... could possibly be treated with butein to prevent cell … 5g 用語解説Webof HTLV-1-infected T-cell lines. T cells cultured with butein showed obvious apoptosis morphology, and cleavage of poly(ADP-ribose) polymerase with activation of caspase-3, -8 and -9. Pretreatment of cells with caspase inhibitor partially blocked butein-induced inhibition of cell viability. Butein also resulted in cell cycle arrest at G 1 phase. 5g 物聯網應用WebIn summary, we revealed a novel mechanism by which butein induced cell cycle arrest and apoptosis in HCC cells. For the first time, Aurora B was validated to be the direct target of butein. By suppressing Aurora B, butein had substantial antitumor activities against HCC in vitro and in vivo. Supplementary Material. Supplementary figures and table. 5g 発信機WebIt was shown that butein reduced NSCLC cells proliferation and induced cell cycle arrest in G2/Mitosis phase through regulating cyclin B1, Cdc25C and Cdc2 expression levels. ... 5g 監視社会WebThe present invention relates to a carbon nanotube dispersion including carbon nanotubes, a polymer dispersant containing an amine, a phenolic compound including two or more aromatic rings, and an aqueous solvent, wherein the polymer dispersant and the phenolic compound including two or more aromatic rings are included in a weight ratio of 100:1 to … 5g 産業用途WebIn ovarian cancer, butein inhibited cell proliferation, migration, and invasion, and induced cell cycle arrest and apoptosis, and decreased the growth of ovarian cancer cells in xenograft tumor models. Butea monosperma (Fabaceae) has been used in traditional Indian medicine to treat a variety of ailments, including abdominal tumors. We aimed to … 5g 発生器