Ctgf lncrna
WebApr 3, 2024 · One of the key mechanisms of cardiac diseases has recently been identified as long non-coding RNA (lncRNA) dysregulation. Through in vitro and in vivo studies, … WebThe etiology of polycystic ovary syndrome (PCOS) is complex and the pathogenesis is not fully understood. Some studies have shown that dysregulation of ovarian granulosa cells may be related to abnormal follicles and excessive androgen in women with PCOS. Our team has also confirmed the high expression status of H19 in PCOS patients in the early …
Ctgf lncrna
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WebDec 30, 2024 · The relative expression levels of lncRNA PVT1, CTGF, E-cadherin and vimentin were analyzed using reverse transfection-quantitative polymerase chain … WebLncRNA MSTRG.15746 and Il6 as well as lncRNA MSTRG.74451 and Il1f9 may have trans-regulatory relationships . These results suggested that lncRNAs and their targeted genes might be associated with the protective effect of itaconate, indicating that the regulatory role of lncRNAs is an ideal entry point to study the mechanism by which …
WebDec 14, 2024 · This study reveals that upregulation of lncRNA small nucleolar RNA host gene 5 (SNHG5), mediated by Yin Yang 1 (YY1), activates connective tissue growth … WebSep 1, 2024 · Download Citation LncRNA TUG1 Acts as a Competing Endogenous RNA to Mediate CTGF Expression by Sponging miR‐133b in Myocardial Fibrosis after Myocardial Infarction Myocardial fibrosis is one ...
WebDec 12, 2024 · During the proliferative phase of diabetic wound healing, lncRNA H19 recruits the transcription factor SRF to the CTGF promoter region, activating CTGF and its downstream MAPK signaling pathway to accelerate fibroblast proliferation and wound healing. These findings elaborate lncRNA H19 as a regulator in the regenerative phase … WebFor example, the lncRNA B4GALT1-AS1 can directly bind to YAP to promote its nuclear translocation, while the lncRNA LEF1-AS1 directly interacts with the LATS1 protein, abolishing the interaction between LATS1 and MOB and leading to inactivation of the Hippo pathway. 61,62 LncRNAs can also indirectly influence the Hippo pathway by interacting ...
WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN …
WebApr 9, 2024 · This has been supported by expression of specific protein-coding genes that facilitate organ-specific metastatic tropism (such as connective tissue growth factor (CTGF) in bone metastases 106 ... ontario building code for deck constructionWebJun 21, 2024 · A lncRNA known as lncRNA megacluster ( lnc-MGC) was found to play a key role in the pathogenesis of early DN ( 72 ). Lnc-MGC is a host gene for miR-379 cluster, i. e., harbors miRNAs in its exonic and intronic sequences and these non-coding RNAs are present within one of the largest miRNA clusters in the genome. iom life insuranceWebOct 7, 2024 · In conclusion, our study indicated that lncRNA H19 acted as a ceRNA to bind to miR-19b via a “sponge” to regulate the effect of CTGF on KGN cells, which may play a … iom lighthousesWebJul 28, 2024 · PDF Cardiac fibrosis is closely related to multiple cardiovascular system diseases, and noncoding RNAs (ncRNAs), including long noncoding RNA (lncRNA)... Find, read and cite all the research ... iom limitedWebSep 3, 2024 · Connective tissue growth factor (CTGF), also referred to as CCN2, belongs to the CCN (acronym for Cyr61, CTGF, ... The lncRNA AK139128 may be involved in this communication during IR, potentially as a regulator of cardiac remodeling. Other lncRNA have also been reported to participate in cardiac IR. iom lighthouse challengeWebMar 9, 2024 · LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR-133b in myocardial fibrosis after myocardial infarction. ... Connective tissue growth factor (CTGF) has been found to be an important downstream mediator of TGF-beta1, and controls pro-fibrotic activities in renal fibrosis. ... ontario building code for barrier free condosWebJan 25, 2024 · Unintended cardiac fibroblast proliferation in many pathophysiological heart conditions, known as cardiac fibrosis, results in pooling of extracellular matrix (ECM) proteins in the heart muscle. Transforming growth factor β (TGF-β) as a pivotal cytokine/growth factor stimulates fibroblasts and hastens ECM production in injured … iom list c