WebHEALEY ALS Platform Trial 8. Perpetual adaptive trial-Open Label Extension offered Screening 1:1:1 Randomization RegimenB Regimen A Regimen C (n=160 for each … WebMar 16, 2024 · Participant is eligible for participation in: (i) the HEALEY ALS Platform trial (NCT04297683), or (ii) any active study investigating CNM-Au8 for the treatment of ALS. Participant has a history of any clinically significant or unstable medical condition (other than ALS) that may interfere with assessment of safety or compromise the study ...
Trial: HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose
WebJan 10, 2024 · Five major trials have results anticipated in 2024, including highly anticipated data from the HEALEY platform study. With only two FDA-approved drugs targeting ALS, there is a glaring unmet need for new treatments. Only generic riluzole, which first gained FDA approval in 1995, shows a modest effect on survival. WebNov 29, 2024 · The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen E will evaluate the safety and efficacy of a single study drug, SLS-005 (Trehalose injection, 90.5 mg/mL for intravenous infusion) in participants with ALS. ... dt630 マスプロ
Denali Therapeutics Announces New DNL343 (eIF2B Agonist) …
WebDec 22, 2024 · Seelos Therapeutics announced that the Seelos’ phase 2b/3 study of SLS-005 (trehalose) has been selected by the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital to be included in the HEALEY ALS Platform Trial, the first ever platform trial for the treatment of amyotrophic lateral sclerosis (ALS). 1 The … WebHealey ALS Platform Trial Regimen E: A Participant’s Guide. View All. Current Trials. Recruiting A Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Biodistribution of an Imaging Agent, 18F-OP-801 (18F Hydroxyl Dendrimer), After Intravenous Administration to Patients With Amyotrophic Lateral Sclerosis (ALS) and Healthy Volunteers (HV) WebMar 5, 2024 · The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment … dt5s デジタルセオドライト