Web14 feb 2024 · 中山大学中山医学院王继厂研究团队发现化学诱导的染色质重塑可将小鼠 ESC 重编程为全能样干细胞 (TLSCs)。 相关论文于2024年2月9日发表在《细胞—干细胞》杂志上。 他们重塑着丝粒周围异染色质并重建全能特异性宽 H3K4me3 结构域的方法促进了多能性向全能性的转变。 他们的方法建立了比任何其他 2C 样细胞更紧密的小鼠 2 细胞 (2C) 胚 … Web18 lug 2013 · We refer to these 2i-competent, ESC-like, and GFP-positive cells as chemically induced pluripotent stem cells (CiPSCs). Next, we optimized the dosages and treatment duration of the small molecules and were able to generate 1 to 20 CiPSC colonies from 50,000 initially plated MEFs (fig. S7).
Hongkui Deng - Publications
WebThe whole chemical reprogramming trajectory analysis delineated the induction of the intermediate plastic state at the early stage, during which chemical-induced … WebHongkui Deng Extended pluripotent stem (EPS) cells have shown great applicative potentials in generating synthetic embryos, directed differentiation and disease modeling. However, the lack of a... lined stretch jeans
Chemical reprogramming: the CiPSCs and the CiNs
WebNational Center for Biotechnology Information WebHongkui Deng - Publications Hongkui Deng - Publications Affiliations: Beijing University, Beijing, Beijing Shi, China Tree Info Grants Similar researchers PubMed Report error 130 high-probability publications. We are testing a new system for linking publications to … WebYaxing Xu's 11 research works with 381 citations and 1,536 reads, including: Derivation of totipotent-like stem cells with blastocyst-like structure forming potential lined study cards