WebThe basis for recommending hormone replacement therapy (HRT) in women at low risk of breast cancer, and the evidence for the benefits and risks associated with its use, can … Webpatients who are taking HRT should be counseled about the increased risk of breast cancer after four to five years of use history or known high risk of venous or arterial …

Sex hormones Treatment summaries BNF NICE

WebBNF Drugs Estradiol with norethisterone Estradiol with norethisterone Navigate to section Constituent drugs Indications and dose Interactions Patient and carer advice Medicinal forms Other drugs in class Interactions View interactions for: Estradiol Hormone replacement therapy Norethisterone Or jump straight to: Tablet Transdermal patch WebHormone replacement therapy, or HRT, is widely used to treat menopausal symptoms. As you approach the menopause, your ovaries produce less and less of the hormone estrogen. Estrogen controls a woman’s reproductive cycle as well as controlling other functions, including bone density, skin temperature and keeping the vagina moist. switching exchange

Tibolone: benefit-risk balance - GOV.UK

WebUnder age 45—uncertain diagnosis Hormone replacement therapy (HRT) HRT choice is based on a number of factors: Patient choice, patient adherence, safety and efficacy Over the counter (OTC) supplements and alternative therapies may be encouraged although, there is no validated evidence of efficacy but there is reported anecdotal evidence. Webno HRT use* (RR= 1) Total cases (range) per 1000 women using HRT† Extra cases per 1000 women using HRT Risk ratio (RR) (95% CI)‡ Cancer risks Breast cancer Overall combined HRT Current use from age 50 5 13 21 +8 1.62 10 27 47 +20 1.74 Total risk from age 50 to 69 (HRT use + past use) 5 63 80 +17 1.27 10 63 97 +34 1.54 Sequential HRT switching error